To prepare Ceftriaxone Injection, first, ensure aseptic conditions. Reconstitute the ceftriaxone injection powder with sterile water or the recommended diluent. For IV use, dissolve 1g in 10mL sterile water and administer slowly over 5 minutes. For IM use, dissolve 1g in 3.5mL of 1% lidocaine and inject deep into the muscle. Always check for compatibility with IV fluids before administration. Shake well until fully dissolved. Inspect for particles or discoloration before use. Follow proper dosage guidelines based on patient condition. Dispose of used materials safely. Always consult healthcare protocols when preparing Ceftriaxone Injection for patient administration.